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Tert

Human Genetics   Research Article

Association of monocyte chemoattractant protein-1 rs1024611 and telomerase rs2736100 polymorphisms with susceptibility to pulmonary tuberculosis in Han Chinese population

Authors: G.H. Cheng, X.L. Wang, X.T. Yuan, Q. Xin, Q. Sun, K.L. Li, C. Sun, Z.M. Lin, Y. Luan, Y.S. Wang, F. Kong and D.W. Xu

Pulmonary tuberculosis (PTB) is caused by Mycobacterium tuberculosis infection and accumulated evidence reveals the genetic context of its infection phenotypes. Monocyte chemoattractant protein-1 (MCP-1) rs1024611 variant is shown to be associated with PTB susceptibility in some studies, but significant disparities exist. In a.. Read More»

Genet. Mol. Res. 16(3):
gmr16039697
DOI:
10.4238/gmr16039697
Animal Genetics   Research Article

Preventive effect of tert-butylhydroquinone on scrotal heat-induced damage in mouse testes

Authors: Y.S. Li1, Y.G. Piao1, K. Nagaoka2,3, G. Watanabe2,3, K. Taya2,3 and C.M. Li1

To investigate the effect of tert-butylhydroquinone (tBHQ) on scrotal heat-induced damage in mice testes, 8-week-old mice were divided into 6 groups and administered with or without tBHQ through diet (10 mg/g), intraperitoneal injection (100 mg/kg body weight), or intratestis injection (12.5 mg/kg body weight), respectively. After single scrotal heat expo.. Read More»

Genet. Mol. Res. 12(4):
2013.November.11.5
DOI:
10.4238/2013.November.11.5
Human Genetics   Research Article

Association of genetic polymorphisms in TERT-CLPTM1L with lung cancer in a Chinese population

Authors: S.G. Liu, L. Ma, Q.H. Cen, J.S. Huang, J.X. Zhang and J.J. Zhang

Genome-wide association studies in several ethnic groups have reported that polymorphisms of the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes, located on 5p15.33, are associated with susceptibility to lung cancer. However, whether genetic variants of TERT-CLPTM1L are associated with an increased ris.. Read More»

Genet. Mol. Res. 14(2):
2015.May.4.4
DOI:
10.4238/2015.May.4.4
Medical Genetics   Research Article

Reason and treatment of failure of proximal femoral nail antirotation internal fixation for femoral intertrochanteric fractures of senile patients

Authors: J.J. Liu, L.C. Shan, B.Y. Deng, J.G. Wang, W. Zhu and Z.D. Cai

The cause of postoperative failure after the treatment of femoral intertrochanteric fracture with proximal femoral nail antirotation (PFNA) was analyzed, and the reoperative methods were examined. Nine failures of 308 femoral intertrochanteric fracture patients with PFNA were treated with femoral prosthesis total hip replaceme.. Read More»

Genet. Mol. Res. 13(3):
2014.August.7.10
DOI:
10.4238/2014.August.7.10
Human Genetics   Research Article

Decreased risk of developing lung cancer in subjects carrying the CLPTM1L rs401681 (G>A) polymorphism: evidence from a meta-analysis

Authors: X.L. Zhang, X.J. Zhang, Y. Chen, Y.M. Zhang, Q. Zhang,C.X. Cao, D.Y. Gu, J.F. Shi, Y.L. Gong, J.F. Chen and C.J. Tang

A genome-wide association study revealed that a single nucleotide polymorphism, CLPTM1L - rs401681 (G>A), located at the 5p15.33 locus was signifi cantly associated with increased risk of various cancers; however, its association with lung cancer is currently inconclusive. In order to explore the relationship between this p.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.28.10
DOI:
http://dx.doi.org/10.4238/2014.February.28.10
Human Genetics   Research Article

Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma

Authors: X.F. Chen, S. Cai, Q.G. Chen, Z.H. Ni, J.H. Tang, D.W. Xu and X.B. Wang

Recent studies have shown that 5p15.33 is one of the chromosomal regions that is most consistently altered in lung cancer; common variants that are located in this region have been genotyped in various populations. However, the genetic contribution of these variants to carcinogenesis is relatively unknown. A clinic-based case-.. Read More»

Genet. Mol. Res. 11(1):
2012.February.16.2
DOI:
10.4238/2012.February.16.2
Microbial Genetics   Research Article

Genetic and biochemical analyses of sensor kinase A in Bacillus subtilis sporulation

Authors: J.C. Nguele, P. Eswaramoorthy, M. Bhattacharya, E. Ngou-Milama and M. Fujita

This paper has been retracted (without the consent of the submitting author, Jean- Calvin Nguele) because of serious fraud and plagiary issues. The submission letter, sent by Jean-Calvin Nguele, included forged signatures of Prahathees Eswaramoorthy, Mou Bhattacharya, and Masaya Fujita. Additionally, the paper contains informa.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr758
DOI:
10.4238/vol9-1gmr758
Microbial Genetics   Research Article

Effect of montelukast on the expression of interleukin-18, telomerase reverse transcriptase, and Bcl-2 in the brain tissue of neonatal rats with hypoxic-ischemic brain damage

Authors: J.L. Liu, X.H. Zhao, D.L. Zhang, J.B. Zhang and Z.H. Liu

The aim of this study was to investigate the effect of montelukast on the expression of interleukin (IL)-18, telomerase reverse transcriptase (TERT), and Bcl-2 in the brain tissue of neonatal rats with hypoxic-ischemic brain damage (HIBD). To establish the model of HIBD, 8% oxygen was applied to rats after the unilateral carotid artery was ligated. Twenty.. Read More»

Genet. Mol. Res. 14(3):
2015.August.3.13
DOI:
10.4238/2015.August.3.13