Tlr4
Association between polymorphisms in TLR4 gene targeted by microRNA-140 and cervical precancerous lesion in south Chinese women: a case control study
Authors: Chuican Huang , Zhongyi Li , Xingming Zhong, Yao Wang, Xingguang Ye, Lipeng Jing, Shiqi Huang, Qian Yin , Zhulin Miao, Zixing Zhou, Yang Liu, Xiaohong Ye, Yajing Han, Meiling Ou, Di Xiao , Congcong Guo, Chengli Zeng, Guang Yang, Chunxia Jing, Xiangcai Wei
Toll-like receptor 4 (TLR4), one of the key immune system effectors, plays a main role in immune recognition of cervical cancer. Micro-RNAs are involved in regulation of multiple important genes in the progression of cervical cancer. A case-control study of 592 people was conducted from Yun’an County, Yunfu City, Guangdo.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039831
- DOI:
- 10.4238/gmr16039831
Sequence characterization and phylogenetic analysis of toll-like receptor (TLR) 4 gene in the Tibetan macaque (Macaca thibetana)
Authors: Q.X. Dai, Y.F. Yao, Z.C. Qi, Y. Huang, Q.Y. Ni, M.W. Zhang and H.L. Xu
In this study, the complete coding region sequence of an innate immune-related TLR4 gene was obtained from the Tibetan macaque (Macaca thibetana) genome via PCR and direct sequencing. The sequence had a total length of 2481 bp, contained 3 complete exons, and encoded 826 amino acids (AAs); its isoelectric point was 5.703, and the molecular weight was 94.7.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.16
- DOI:
- 10.4238/2015.March.13.16
Association of bovine Toll-like receptor 4 with tick infestation rates and blood histamine concentration
Authors: G. Zhao1,2, M. Yu, Q.-W. Cui, X. Zhou, J.-C. Zhang, H.-X. Li, K.-X. Qu, G.-L. Wang and B.-Z. Huang
We investigated a possible association between bovine Toll-like receptor 4 (TLR4) and resistance to tick infestation in 103 cattle, including BMY cattle (1/2 Brahman, 1/4 Murray Grey, and 1/4 Yunnan Yellow cattle), Brahman, and Red Angus grazing on improved pasture. The tick infestation weight and number of Rhipicephalus microplus and the blood histamine .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.21
- DOI:
- 10.4238/2013.February.28.21
Association between polymorphisms in ADAM33, CD14, and TLR4 with asthma in the Uygur population in China
Authors: J. Wang, M. Simayi, Q. Wushouer, Y. Xia, Y. He, F. Yan, J. Zhang, S. Cui and H. Wen
We evaluated the associations between single nucleotide polymorphisms (SNPs) and haplotypes of the genes encoding a disintegrin and metalloproteinase 33 (ADAM33), cluster of differentiation 14 (CD14), and Toll-like receptor 4 (TLR4) and the susceptibility of developing specific adult phenotypes of bronchial asthma in a Chinese.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.June.18.11
- DOI:
- 10.4238/2014.June.18.11
TLR4 gene expression in pig populations and its association with resistance to Escherichia coli F18
Authors: J. Wang, Z.Y. Pan, X.R. Zheng, Z.C. Wu, X.M. Su, G.Q. Zhu, X.G. Huang, S.L. Wu and W.B. Bao
TLR4 is the main recognition receptor of bacterial lipopolysaccharides, which play an important role in innate and adaptive immunity. We used real-time PCR to analyze the tissue expression profile and differential expression of TLR4 in 4 pig populations (Escherichia coli F18-resistant Sutai, E. coli F18-sensitive Sutai, Large White, Meishan), in order to .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.30.1
- DOI:
- 10.4238/2013.July.30.1
Single nucleotide polymorphisms in immunity-related genes and their association with mastitis in Chilean dairy cattle
Authors: A.M. Carvajal, P. Huircan and A. Lepori
Mastitis remains a major cattle disease with great global economic implications. Various approaches are currently employed in attempts to improve understanding of mastitis resistance and develop phenotypic markers for use in breeding programs (e.g., somatic cell score), including QTL discovery, wide-genome association studies, and identification of candid.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.30.8
- DOI:
- 10.4238/2013.July.30.8
Relationship between TLR4 and MCP2 expression levels and habitual abortion
Authors: X.P. Li, L.N. Song, L.P. Tian and Y.S. Zhang
Habitual abortion is associated with the altered expression of multiple genes. This study was carried out to investigate the relationship between expression of Toll-like receptor 4 (TLR4) and monocyte chemotactic protein 2 (MCP2 or CCL8) and habitual abortion. This was done by detecting and comparing their relative expression .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027378
- DOI:
- 10.4238/gmr.15027378