Transcription Factor
Bioinformatic analyses of GRAS genes in Betula kirghisorum based on transcriptome data
Authors: C.J. Yang, G.Y. Li and Y.L. Cui
The transcriptomes of salt-stressed and unstressed Betula kirghisorum plants were analyzed using high throughput sequencing technology. A total of 52,239,804 and 51,772,998 clean reads were obtained from the two libraries, respectively, and de novo assembled into 60,545 all-unigenes. A total of 39,997 unigenes were annotated using public databases. Overal.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038321
- DOI:
- 10.4238/gmr.15038321
Characterization of RsMYB28 and RsMYB29 transcription factor genes in radish (Raphanus sativus L.)
Authors: X.B. Luo, Z. Liu, L. Xu, Y. Wang, X.W. Zhu, W. Zhang, W. Chen, Y.L. Zhu, X.J. Su, M. Everlyne and L.W. Liu
Glucosinolates (GSLs) are important secondary metabolites in Brassicaceae plants. Previous studies have mainly focused on GSL contents, types, and biosynthesis-related genes, but the molecular characterization patterns of GSL biosynthesis-related transcription factors remain largely unexplored in radish (Raphanus sativus L.). To isolate transcription fact.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038381
- DOI:
- 10.4238/gmr.15038381
In silico identification and characterization of the WRKY gene superfamily in pepper (Capsicum annuum L.)
Authors: Y. Cheng, Z.P. Yao, M.Y. Ruan, Q.J. Ye, R.Q. Wang, G.Z. Zhou, J. Luo, Z.M. Li, Y.J. Yang and H.J. Wan
The WRKY family is one of the most important transcription factor families in plants, involved in the regulation of a broad range of biological roles. The recent releases of whole-genome sequences of pepper (Capsicum annuum L.) allow us to perform a genome-wide identification and characterization of the WRKY family. In this study, 61 CaWRKY proteins were .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038675
- DOI:
- 10.4238/gmr.15038675
Genome-wide identification and characterization of the Dof gene family in Medicago truncatula
Authors: Y.J. Shu, L.L. Song, J. Zhang, Y. Liu and C.H. Guo
The DNA-binding one zinc finger (Dof) family is a classic plant-specific zinc-finger transcription factor family, which is involved in many important processes, including seed maturation and germination, plant growth and development, and light responses. Investigation of the Medicago truncatula genome revealed 42 putative Dof genes, each of which holds on.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.5
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.5
Biochip analysis of prostate cancer
Authors: M.Q. Fan, P.X. Wang, J.Y. Feng, Y. Xiao and C.B. Huang
Microarray expression analysis was used to forecast the roles of differentially co-expressed genes (DCG) and DCG and links in the pathogenesis of prostate cancer. In addition, we demonstrate that the relationship between transcriptional factors (TFs) and their targets can be considered a key factor in determining the differenc.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.10.6
- DOI:
- 10.4238/2014.January.10.6
Agrobacterium-mediated transformation of tomato with the ICE1 transcription factor gene
Authors: J.X. Juan, X.H. Yu, X.M. Jiang, Z. Gao, Y. Zhang, W. Li,Y.D. Duan and G. Yang
ICE1 genes play a very important role in plants in cold conditions. To improve the cold resistance of tomato, the ICE1 gene of Arabidopsis thaliana was used to construct the plant expression vector p3301-ICE1, and was overexpressed in tomato through Agrobacterium-mediated transformation. Five strains of resistant plants were obtained. PCR and half-quantitati.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.1
- DOI:
- 10.4238/2015.January.30.1
E2F, HSF2, and miR-26 in thyroid carcinoma: bioinformatic analysis of RNA-sequencing data
Authors: J.C. Lu and Y.P. Zhang
In this study, we examined the molecular mechanism of thyroid carcinoma (THCA) using bioinformatics. RNA-sequencing data of THCA (N = 498) and normal thyroid tissue (N = 59) were downloaded from The Cancer Genome Atlas. Next, gene expression levels were calculated using the TCC package and differentially expressed genes (DEGs) were identified using the ed.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017576
- DOI:
- 10.4238/gmr.15017576
GmPTF1, a novel transcription factor gene,is involved in conferring soybean tolerance to phosphate starvation
Authors: X.H. Li, B. Wu, Y.B. Kong and C.Y. Zhang
Phosphorus plays a pivotal role in plant growth and development. In this study, we isolated and characterized GmPTF1, a basic helix-loop-helix (bHLH) transcription factor (TF) gene from soybean (Glycine max) with tolerance to inorganic phosphate (Pi) starvation. Alignment analysis indicated that GmPTF1 and other reported bHLH .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.February.19.3
- DOI:
- 10.4238/2014.February.19.3
Cloning and expression pattern analysis of BkGRAS2 from Betula kirghisorum
Authors: G.Y. Li, C.J. Yang and G.J. Liu
GRAS proteins are plant-specific transcription factors that are involved in the regulation of root and shoot growth. Here, we cloned BkGRAS2 from Betula kirghisorum (abbreviated to Bk) and analyzed the physicochemical properties and expression pattern of the encoded protein. BkGRAS2 had an open reading frame of 1614 bp encoding 537 amino acid residues. Th.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.22.27
- DOI:
- http://dx.doi.org/10.4238/2015.September.22.27
Novel NKX2-5 mutations responsible for congenital heart disease
Authors: J. Wang, X.Y. Liu and Y.Q. Yang
Congenital heart disease (CHD) is the most common birth defect and is the leading cause of infant morbidity and mortality resulting from birth defects. Increasing evidence demonstrates that genetic variation in the NKX2-5 gene, which encodes a homeobox-containing transcription factor crucial to cardiogenesis, is an important m.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.29.1
- DOI:
- 10.4238/2011.November.29.1