Transcription Factor
Transcription factors expressed in soybean roots under drought stress
Authors: S.S. Pereira, F.C.M. Guimar�£es, J.F.C. Carvalho, R. Stolf-Moreira, M.C.N. Oliveira, A.A.P. Rolla, J.R.B. Farias, N. Neumaier and A.L. Nepomuceno
To gain insight into stress-responsive gene regulation in soybean plants, we identified consensus sequences that could categorize the transcription factors MYBJ7, BZIP50, C2H2, and NAC2 as members of the gene families myb, bzip, c2h2, and nac, respectively. We also investigated the evolutionary relationship of these transcript.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.21.5
- DOI:
- 10.4238/2011.October.21.5
Diagnosis of lymph node micrometastasis at the pN0 stage of lung adenocarcinoma using a combination of markers
Authors: H. Liu, Y.-K. Ye, G.-M. Li, Y. Zhou, K.-B. Han, G. Xu and D. Wang
This study aimed to detect micrometastatic tumor cells in the lymph nodes of patients with pN0 lung adenocarcinoma using a combination of thyroid transcription factor-1 (TTF-1) expression and cytokeratin 7 (CK7) expression and to investigate the association of lymph node micrometastasis with the clinicopathological characteris.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.14
- DOI:
- 10.4238/2014.July.25.14
Transcription factor 7-like 2 polymorphisms and diabetic retinopathy: a systematic review
Authors: P. Sudchada and K. Scarpace
The global prevalence of type 2 diabetes mellitus (T2DM) has increased, as well as complications including diabetic retinopathy. Polymorphisms in transcription factor 7-like 2 (TCF7L2) have been associated with T2DM, with the strongest association attributed to the single-nucleotide polymorphism rs7903146. In this rev.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.1
- DOI:
- 10.4238/2014.August.7.1
A comparative analysis of highly conserved sex-determining genes between Apis mellifera and Drosophila melanogaster
Authors: Alexandre S. Cristino, Adriana Mendes do Nascimento, Luciano da Fontoura Costa and Zil�¡ Luz Paulino Sim�µes
A comparison of the most conserved sex-determining genes between the fruit fly, Drosophila melanogaster, and the honey bee, Apis mellifera, was performed with bioinformatics tools developed for computational molecular biology. An initial set of protein sequences already described in the fruit fly as participants of the sex-det.. Read More»
- Genet. Mol. Res. 5(1):
Correlation of the TCF7L2 (rs7903146) polymorphism with an enhanced risk of type 2 diabetes mellitus: a meta-analysis
Authors: Y. Guan, L.H. Yan, X.Y. Liu, X.Y. Zhu, S.Z. Wang and L.M. Chen
Increasing evidence has demonstrated that a transcription factor 7-like 2 (TCF7L2) polymorphism (rs7903146) is significantly associated with type 2 diabetes mellitus (T2DM); however, limited sample size and variance of ethnicity in the studies investigating this association have led to conflicting reports regarding its role. Therefore, a comprehensive met.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037969
- DOI:
- 10.4238/gmr.15037969
Oxidative stress response in Paracoccidioides brasiliensis
Authors: Ã?Â?lida G. Campos, RosÃ?¡lia Santos Amorim Jesuino, Alessandra da Silva Dantas, Marcelo de Macedo BrÃ?Âgido and Maria Sueli S. Felipe
Survival of pathogenic fungi inside human hosts depends on evasion from the host immune system and adaptation to the host environment. Among different insults that Paracoccidioides brasiliensis has to handle are reactive oxygen and nitrogen species produced by the human host cells, and by its own metabolism. Knowing how the pa.. Read More»
- Genet. Mol. Res. 4(2):
Overexpression of the activated form of the AtAREB1 gene (AtAREB1Ã?Â?QT) improves soybean responses to water deficit
Authors: J.P. Leite, E.G.G. Barbosa, S.R.R. Marin, J.P. Marinho, J.F.C. Carvalho, R.F. Pagliarini, A.S. Cruz, M.C.N. Oliveira, J.R.B. Farias, N. Neumaier, F.C.M. Guimar�£es, T. Yoshida, N. Kanamori, Y. Fujita, K. Nakashima, K.Y. Shinozaki, J.A. Desid�©rio and A.L. Nepomuceno
Abscisic acid-responsive element binding protein (AREB1) is a basic domain/leucine zipper transcription factor that binds to the abscisic acid (ABA)-responsive element motif in the promoter region of ABA-inducible genes. Because AREB1 is not sufficient to direct the expression of downstream genes under non-stress conditions, a.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.15.10
- DOI:
- 10.4238/2014.August.15.10
MYBA2 gene involved in anthocyanin and flavonol biosynthesis pathways in grapevine
Authors: T.Q. Niu, Z.D. Gao, P.F. Zhang, X.J. Zhan, M.Y. Gao, W. Ji, W.X. Fan and P.F. Wen
MYBA2 transcription factor (Myb-related gene) affects the coloring in grapevine berry and plays an important role in the biosynthesis of anthocyanin. The MYBA2 gene was cloned from Vitis vinifera L. cv. Cabernet Sauvignon and polyclonal antibodies for VvmybA2 were prepared. The VvmybA2 gene expression patterns were observed in.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048922
- DOI:
- 10.4238/gmr15048922
Regulation of WNK4 gene transcription in the kidneys
Authors: Z.J. Sun, Y. Li, Y.H. Li, J.S. Zhang, Q. Ding, J. Li-Ling, Y. Liang and Y.Y. Zhao
With-no-lysine (K) kinase-4 (WNK4) is a newly cloned kinase-encoding gene that plays a crucial role in the maintenance of electrolyte homeostasis. Mutations of WNK4 can cause pseudohypoaldosteronism type α, an autosomal dominant disease characterized by hyperkalemia, metabolic acidosis and hypertension. We explored the expression and regulatory mech.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.4.9
- DOI:
- 10.4238/2013.January.4.9
Transcriptome network-based method to identify genes associated with unruptured intracranial aneurysms
Authors: L. Wei, Y.J. Gao, S.P. Wei, Y.F. Zhang, W.F. Zhang, J.X. Jiang, Z.Y. Sun and W. Xu
Intracranial aneurysm is a balloon or sac-like dilatation of blood vessels inside the brain. Despite their importance, the biological mechanisms of intracranial aneurysms are not totally understood. We used public genome-wide gene expression profile data to identify potential genes that are involved in intracranial aneurysm in order to construct a regulat.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.2
- DOI:
- 10.4238/2013.September.3.2