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Transcription Factor

Plant Genetics   Research Article

Genome-wide analysis of TCP family in tobacco

Authors: L. Chen, Y.Q. Chen, A.M. Ding, H. Chen, F. Xia, W.F. Wang and Y.H. Sun

The TCP family is a transcription factor family, members of which are extensively involved in plant growth and development as well as in signal transduction in the response against many physiological and biochemical stimuli. In the present study, 61 TCP genes were identified in tobacco (Nicotiana tabacum) genome. Bioinformatic.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027728
DOI:
10.4238/gmr.15027728
Human Genetics   Research Article

Relationship between TBX20 gene polymorphism and congenital heart disease

Authors: X.F. Yang, Y.F. Zhang, C.F. Zhao, M.M. Liu, J.P. Si, Y.F. Fang,W.W. Xing and F.L. Wang

Congenital heart disease in children is a type of birth defect. Previous studies have suggested that the transcription factor, TBX20, is involved in the occurrence and development of congenital heart disease in children; however, the specific regulatory mechanisms are yet to be evaluated. Hence, this study aimed to evaluate th.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027374
DOI:
10.4238/gmr.15027374
Microbial Genetics   Research Article

OsMYB511 encodes a MYB domain transcription activator early regulated by abiotic stress in rice

Authors: P. Huang, H. Chen, R. Mu, X. Yuan, H.S. Zhang and J. Huang

The MYB-domain proteins exist universally across diverse organisms and regulate numerous processes during the plant life cycle. In the present research, a full-length MYB gene OsMYB511 was identified from rice seedlings through microarray data. Induction of OsMYB511 by cold stress was dramatic in japonica cultivar Jiucaiqing as compared to indica IR26. In.. Read More»

Genet. Mol. Res. 14(3):
2015.August.14.14
DOI:
10.4238/2015.August.14.14
Human Genetics   Research Article

Genetic expression and functional characterization of the RUNX2 gene in human adult bone marrow mesenchymal stem cells

Authors: J.Y. Zhang and L.C. Li

Past studies have revealed the critical role of runt-related transcription factor 2 (RUNX2) in the proliferation and differentiation of mesenchymal stem cells (MSCs). This study therefore aimed to investigate the expression profile of the RUNX2 gene in human bone marrow MSCs and its biological characteristics. Bone marrow MSCs were separated from 12 patie.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.8
DOI:
10.4238/2015.December.23.8
Human Genetics   Research Article

Data integration for identification of important transcription factors of STAT6-mediated cell fate decisions

Authors: M. Jargosch, S. Kr�¶ger, E. Gralinska, U. Klotz, Z. Fang, W. Chen, U. Leser, J. Selbig, D. Groth and R. Baumgrass

Data integration has become a useful strategy for uncovering new insights into complex biological networks. We studied whether this approach can help to delineate the signal transducer and activator of transcription 6 (STAT6)-mediated transcriptional network driving T helper (Th) 2 cell fate decisions. To this end, we performe.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028493
DOI:
10.4238/gmr.15028493
Microbial Genetics   Research Article

Cloning and stress response analysis of the PeDREB2A and PeDREB1A genes in moso bamboo (Phyllostachys edulis)

Authors: H.L. Wu, L. Li, Z.C. Cheng, W. Ge, J. Gao and X.P. Li

Moso bamboo is a large woody bamboo with the highest ecological, economic, and cultural value among all bamboos in Asia. However, environmental stress influences its growth and development and limits its geographic distribution. Therefore, improving its resistance to environmental stress is extremely important. Dehydration responsive element binding (DREB.. Read More»

Genet. Mol. Res. 14(3):
2015.August.28.4
DOI:
10.4238/2015.August.28.4