Vitamin D
Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population
Authors: X.P. Hu, Z.Q. Li, J.Y. Zhou, Z.H. Yu, J.M. Zhang and M.L. Guo
Environmental influences on the development and progression of dental caries are well known; however, there is little evidence of a genetic component imparting susceptibility to dental caries. The aim of this study was to investigate the relationship between a single nucleotide polymorphism in the vitamin D receptor TaqI locus and dental caries susceptibi.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.15
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.15
Assessment of the link between Vitamin D receptor TaqI gene polymorphism and periodontitis: a meta-analysis in a Chinese population
Authors: X.W. Ji, Y. Wang, C. Cao and L.J. Zhong
Although a number of studies have been conducted to determine the association between vitamin D receptor (VDR) TaqI polymorphism and periodontitis in the Chinese population, this association remains elusive. To assess the influence of VDR TaqI polymorphism on the risk of periodontitis, a meta-analysis was performed in a Chines.. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048883
- DOI:
- 10.4238/gmr.15048883
Expression of �²-defensins in intestines of chickens injected with vitamin D3 and lipopolysaccharide
Authors: L. Lu, S.M. Li, L. Zhang, X.Q. Liu, D.Y. Li, X.L. Zhao and Y.P. Liu
The objective of this study was to evaluate the effect of vitamin D3 (VD3) on the regulation of chicken intestinal b-defensin genes under normal and lipopolysaccharides (LPS) conditions. Four treatment groups were used, including a negative control group, VD3-injection group, LPS-injection group, and both VD3-injection and LPS-injection group. At 4, 24, a.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.13.12
- DOI:
- http://dx.doi.org/10.4238/2015.April.13.12
Reversal effect of vitamin D on different multidrug-resistant cells
Authors: M. Yan and H. Nuriding
We investigated the reversal effect of vitamin D on the multidrug-resistant leukemic Jurkat/ADR and K562/ADR cell lines and conducted a preliminary investigation of its reversal mechanism. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method was used to detect the reversal effect of vitamin D on multid.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.15.6
- DOI:
- 10.4238/2014.August.15.6
Dual role of vitamin D-binding protein 1F allele in chronic obstructive pulmonary disease susceptibility: a meta-analysis
Authors: M. Xiao, T. Wang, T. Zhu and F. Wen
Vitamin D-binding protein (DBP), a highly polymorphic serum protein, encoded by GC gene, is important in the development of chronic obstructive pulmonary disease (COPD). This meta-analysis was performed to assess the association between GC polymorphisms (1F, 1S, and 2 alleles) and COPD susceptibility. Published case-control studies were retrieved from the.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.1
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.1
Vitamin D receptor FokI gene polymorphism and tuberculosis susceptibility: a meta-analysis
Authors: Y.P. Sun and Q.S. Cai
Numerous studies have evaluated the association between FokI polymorphisms in the vitamin D receptor (VDR) gene and tuberculosis risk. However, the specific association remains controversial. In this study, we performed a meta-analysis to assess the association between the VDR gene FokI polymorphism and tuberculosis. Published studies from the PubMed and .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.9.1
- DOI:
- 10.4238/2015.June.9.1
Vitamin D receptor gene FokI, TaqI, BsmI, and ApaI polymorphisms and susceptibility to pulmonary tuberculosis: a meta-analysis
Authors: Y.H. Lee and G.G. Song
The aim of this study was to determine whether vitamin D receptor (VDR) genetic polymorphisms are associated with the susceptibility to pulmonary tuberculosis (PTB). MEDLINE and Embase databases and manual literature searches were used. A meta-analysis was conducted on the associations between the VDR FokI, TaqI, BsmI, and ApaI polymorphisms and PTB susce.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.21
- DOI:
- 10.4238/2015.August.7.21
Association of vitamin D receptor BsmI gene polymorphism with risk of low bone mineral density in post-menopausal women: a meta-analysis
Authors: C. Ma, Q.L. Zhou, Y.J. Deng, X. Liang, D.P. Wu and Y.Z. Dong
The vitamin D receptor BsmI gene polymorphism is reportedly associated with low bone mineral density (BMD) in postmenopausal women, but results from previous studies are conflicting. In the present study, we investigated the association between this polymorphism and the risk of low BMD through a meta-analysis of published stud.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.17
- DOI:
- 10.4238/2014.September.26.17
Active vitamin D3, 1,25-(OH)2D3, protects against macrovasculopathy in a rat model of type 2 diabetes mellitus
Authors: R. Ma, X.L. Deng, G.L. Du, C. Li, S. Xiao, Y. Aibibai and J. Zhu
To investigate the protective effect of the active form of vitamin D3, 1,25-(OH)2D3, on macrovasculopathy in rats with type 2 diabetes mellitus (T2DM), 8-week-old male Sprague-Dawley rats were randomly divided into control group, T2DM group, and treatment group. The T2DM model was established after 6 weeks by administering an .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028113
- DOI:
- 10.4238/gmr.15028113