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Voltage Gated Sodium Channel

Medical Genetics   Research Article

Expression of HCN and sodium channels in murine model of Type I diabetes

Authors: Anantha Maharasi Rama Krishnan and Kavitha Sankaranarayanan

Pancreatic apoptosis is an important event in the pathogenesis of Type 1 Diabetes. It is characterized by secretion and binding of inflammatory cytokines to the pancreatic islets, that activate downstream signaling mechanism. These signaling mechanisms finally increase intracellular calcium level and that lead to the activation of apoptotic pathways. Ion .. Read More»

Genet. Mol. Res. 18(2):